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World Stem Cell Summit 2016

Date: December 6-8, 2016
Location: West Palm Beach, FL


Southwest Embryology Summit

Date: January 6-7, 2017
Location: Phoenix, AZ


The Latest From Our Blog View All

Providing a Logistics Management Solution for Biologic Commodity Transport

Autologous cell and gene therapy processes start and end with the patient, so the transport and storage of these biologic materials pose complex logistical challenges. Depending on the severity of the patient’s illness, there may be limited opportunities for sample collection and, consequently, manufacture of the potential therapy. Furthermore, any variation in temperature or any interruption in the supply chain, can delay delivery and administration of the therapy to the patient. Irregularities in the cold chain may also affect clinical trial results by compromising data integrity as well as product efficacy and safety. To address these challenges, Cryoport and Database Integrations have launched an integrated solution to manage patient and manufacturer scheduling logistics at every stage of the supply chain for both clinical trial and commercialization processes. 

Outsourcing Dewar Management to Improve Human and Animal Health Operations

Today, an increasing number of therapeutics and vaccines for human and animal administration require shipment in specialized shipping containers often referred to as dewars or cryoshippers. Dewars are composed of an aircraft-grade aluminum exterior that protects an inner holding chamber. The inner chamber is surrounded by a high-surface, low-density open cell plastic foam that retains -196 Celsius for up to 10 days to provide the right conditions for temperature-sensitive materials during transport. Because dewars combine advanced packaging, cryogenics and high-vacuum technology, they can be rather expensive to purchase and maintain. Since they are more expensive than a typical shipping container, such as a Styrofoam or cardboard box, dewars need to be returned for cleaning, reconditioning, testing, revalidation and reuse after each shipment. For companies with large dewar fleets, ranging from hundreds to thousands, ensuring that the dewars are returned can be an especially daunting challenge.