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Why Evaporative Cooling Shippers Are Not Optimal for Pharmaceutical Applications in the 2-8°C Range

Evaporative cooling uses evaporation from a pocket of fluid to achieve cooling inside a shipping container, often targeting the 2-8°C range. Although it might be useful for situations with less than stringent requirements—say on shipment of dairy products or food ingredients−it is not a good fit for pharmacetuical or health care applications where strict Chain of Conditions needs to be maintained at all times.

Can You Ship Biological Samples Currently Stored or Shipped with Dry Ice (-0 to -80°C) in Cryoport’s Dry Vapor Shipper at -150°C?

The short answer is: YES!

If a specimen or biological material can transition through the freezing point — as happens when frozen in refrigerators and/or packed in dry ice — then holding it at liquid nitrogen temperatures will not harm the specimen. In fact, it will most likely have a positive impact. Cryoport’s Global Cryogenic Shipping Solution is specifically developed to sustain temperatures below the glass point (-136°C). This means all metabolic processes and certain degradative reactions will cease at these lower temperatures, which will extend the viability and function of the specimen.