Today, there is more focus than ever on temperature monitoring. With increased fragility of biologics and increased scrutiny on maintaining temperature budgets, it is critical that frozen shippers not only maintain their temperature budgets but also have the data to prove it.
Cryoport features a built-in data logger with data analysis available on every shipment. The data-logging temperature probe is in the vapor plug of the Dewar for the most accurate reading available. The temperature mapping includes inside the chamber (which is closest to the actual biomaterial) and the external temperature. This reading combined with the mapping of every shipment check-in point provides a holistic view of the journey. Consequently, every shipment has a full chain-of-custody and chain-of-condition available with both data monitoring and analysis.
Chain-of-Condition
The data monitoring starts with a custom built data logger. The data logger is uniquely positioned with a temperature gauge inside the plug of the specimen chamber. This ensures (unlike other loggers that measure temperatures in the packaging) that this data monitor gets a more accurate reading of the specimen.
The data logger can be set up to report during the shipment and/or after the shipment. For those shipments involving biologics, clinical trials or any other material that needs to be verified before receiving, the data logger can be pulled out and downloaded to the data station. After the shipment, the data logger is automatically removed for data download and analysis.
Chain-of-Custody
The data monitor and analysis also provides a chain of custody when overlaid with the carrier check-ins. The report from the data monitor serves as analysis for temperature monitoring the entire shipment and a tampering warning. Each time the container is opened there will be a temperature record. The report will identify outlier temperature excursions such as opening the shipment in customs or tampering.