Cryogenic (below -150°C) Shipping Systems

Cryogenic Shipping Systems

World-Leading LN2 Dry Vapor Shipping Solutions for the ≤-150°C Temperature Band

Cryoport Systems offers the most advanced cryogenic shipping solutions in the industry, delivering unrivaled reliability, security, and compliance for transporting sensitive biologic materials worldwide. Our cryogenic shipping systems use innovative LN2 dry vapor technology to maintain cryogenic temperatures of -150°C or lower, ensuring product integrity over transit times of up to 10 days.

Whether you are moving regenerative medicine products, pre-frozen cellular therapies, or other cryogenically preserved materials, our cryogenic shipping solutions provide a proven, cost-effective, and risk-averse path to success. With advanced condition monitoring, global tracking, and industry-leading decontamination protocols, we make sure your most valuable materials arrive safely, every time.

 

From our Veri-Clean process to robust requalification of shipping systems before every use, Cryoport Systems sets the standard for quality and safety in the temperature-controlled supply chain.

Our Cryogenic Shipping Systems

Flexible, Reliable, and Engineered for Your Needs

Cryoport Express® cryogenic shipping systems are engineered for performance, flexibility, and regulatory compliance, giving you peace of mind when transporting delicate, high-value materials. Our reusable, LN₂ dry vapor shippers are designed to meet the rigorous demands of the life sciences industry and come backed by integrated condition monitoring and global logistics support.

Whether you need a small-volume shipper, a high-volume solution, or a versatile system that integrates custom collection kits, Cryoport Systems has you covered. Explore our portfolio of cryogenic shipping systems below to find the right match for your operational needs.

  • Cryoport Express® Standard Shipping System

    A versatile, cost-effective cryogenic solution for shipping pre-frozen cellular therapies, stem cells, and other biologics, with up to 10 days of hold time and real-time condition monitoring.

    Learn More

  • Cryoport Express® Combo Shipping System

    Combines cryogenic and controlled temperature capabilities in one system, supporting multiple product types and offering seamless transport for complex shipments.

    Learn More

  • Cryoport Express® HV3 Shipping System

    Designed for larger-volume shipments, the HV3 system delivers extended hold times and optimized capacity, making it ideal for transport of cryogenically preserved materials.

    Learn More

  • Cryomax® Shipping System

    An advanced cryogenic shipper engineered for lab moves and other high-volume needs with maximum payload efficiency and extended duration, providing high-volume, cost-effective performance across global supply chains.

    Learn More

Engineered for Compliance, Visibility, and Peace of Mind

Explore the Advantages of our Cryogenic Shipping Systems

When shipping ultra-sensitive materials at cryogenic temperatures, you need a logistics partner who understands the stakes. Cryoport Systems integrates advanced technology, rigorous compliance, and comprehensive monitoring to reduce risk and elevate confidence in every shipment. With our proprietary Cryoportal® 2 platform, users gain full visibility and traceability of their shipments, backed by the Smartpak™ Condition Monitoring System and supported by Cryoport’s global logistics expertise. From our facility to your destination, you can count on a seamless, secure process every step of the way. From our cutting-edge technology to our rigorous compliance and unwavering reliability, Cryoport Systems is the trusted choice for shipping sensitive materials worldwide.

Advanced Dry Vapor Technology

Maintain Ultra-Low Temperatures Without Free Liquid Nitrogen

Cryoport Systems uses LN₂ dry vapor technology that keeps shipments at ≤-150°C for up to 10 days, eliminating the risks associated with free liquid nitrogen. This technology ensures stable, consistent temperatures across the entire payload, protecting the integrity of sensitive biologic materials. Because the shipper contains only dry vapor, it complies with IATA standards for non-hazardous materials, simplifying handling and reducing costs.

Veri-Clean® Decontamination Process

Extensive Cleaning and Decontamination for Every Shipper, Every Time

Each Cryoport Express® shipper undergoes our proprietary Veri-Clean® decontamination procedure before each use, ensuring no cross-contamination or residue from prior use. Veri-Clean® uses validated disinfecting agents and processes to thoroughly sanitize the interior and exterior of each shipper, as well as all stainless steel accessories. This commitment to cleanliness safeguards the purity and safety of your biologic materials, providing confidence and compliance with global standards.

Learn More about Veri-Clean

Smartpak™ Condition Monitoring

Continuous Monitoring and Data

Our Smartpak™ system offers near real-time tracking of each shipment, including temperature, orientation, shock, and location data. Our team of logistics experts monitor shipments live via the Cryoportal® 2 platform, receiving proactive alerts if any anomalies occur, allowing for swift intervention if needed. All shipment data is archived in the Cryoportal, will full track and trace for every shipment.

Learn More about Continuous Monitoring

Chain of Compliance®

Complete Traceability Across Equipment, Materials, and Processes

Cryoport’s proprietary Chain of Compliance® ensures that every shipment is fully traceable, from equipment preparation to final delivery. Using Cryoportal® 2, clients can view detailed records, including shipper history, decontamination certificates, temperature logs, and transport routes. This unmatched visibility reduces regulatory risk, simplifies documentation, and supports high-stakes submissions and audits.

Learn More about Chain of Compliance

Global Reach with Local Support

Seamless Regional and International Shipping Solutions

Cryoport Systems operates a global logistics network with regional hubs and strategic partners, enabling reliable, efficient transport across borders. Our team provides expert customs and trade support, helping you navigate complex international requirements and avoid costly delays. From regional couriers to international freight, we deliver consistent quality and performance no matter where your materials need to go.

Trusted Across Diverse Life Sciences Sectors

Cell & Gene Therapy (CGT)
Cryoport Systems was purpose-built to support the life sciences. Today, our partnership capabilities have grown to include not only our expert temperature-controlled supply chain logistics, but to encompass an end-to-end platform encompassing BioServices and biostorage, cryopreservation, and custom-tailored risk mitigation and consulting services.

Learn More

Reproductive Medicine
Cryoport Express® systems are relied upon by fertility clinics, IVF centers, and reproductive medicine providers worldwide to transport precious reproductive materials, including embryos, oocytes, and sperm. Our rigorous standards and continuous monitoring help protect viability and give intended parents and clinicians peace of mind.

Learn More

Animal Health
For the veterinary and animal health industries, our cryogenic shipping solutions support the secure transport of critical materials, including animal gametes, embryos, and regenerative therapies. Whether for research, breeding programs, or therapeutic applications, we provide the precision and compliance necessary to protect valuable animal health assets.

Learn More