Cryoport Express® C3™

Shipping System

Cryoport Express® C3™ Shipping System

Intelligent protection for 2–8°C and 15–25°C shipments in the life sciences.

Cryoport’s C3™ Shipping System is the most advanced temperature-controlled solution on the market for transporting life sciences materials at Refrigerated (2–8°C) or Controlled Room Temperature (15–25°C) ranges. Designed to meet the demanding requirements of pharmaceutical, biologic, and diagnostic shipments, the C3™ combines robust packaging performance with intelligent monitoring and 24/7/365 support.

With integrated Smartpak™ Condition Monitoring and continuous monitoring via the Cryoportal® Logistics Management Platform, the C3™ enables complete oversight, intervention capability, and full Chain of Compliance®. Whether used for clinical trial distribution or commercial logistics, C3™ ensures that your temperature-sensitive payloads stay within range and on track.

From our Veri-Clean® process to robust requalification of shipping systems before every use, Cryoport Systems sets the standard for quality and safety in the temperature-controlled supply chain.

Advanced Design. Assured Compliance.

The C3™ delivers more than temperature control, it delivers confidence.

The C3™ is engineered for reliability, data integrity, and consistent performance across all shipment conditions. Durable, ISTA 3A-compliant components protect the payload during transit, while serialized phase change panels maintain target temperatures with minimal deviation. From planning through delivery, the system provides complete traceability and documentation to meet regulatory requirements with confidence.

Dual-Temperature Flexibility (2–8°C or 15–25°C)

Whether your shipment requires cold chain storage or ambient conditions, the C3™ system offers validated performance for both Refrigerated and Controlled Room Temperature ranges.

One system. Two ranges. Maximum utility.

Choose the configuration you need, with full confidence in temperature hold time and thermal stability.

Smartpak™ Condition Monitoring System

Every C3™ shipper is embedded with our Smartpak system, continuously tracking key metrics: temperature, location, orientation, shock, humidity, pressure, battery life, and tamper events.

Critical insight in every shipment.

Smartpak enables proactive risk mitigation and provides a full audit trail for compliance and quality assurance.

Cryoportal® Logistics Management Platform

The Cryoportal Platform gives you full visibility, control, and documentation from end to end. Integrated with Smartpak, it centralizes shipment data and supports ordering, reporting, and audit readiness.

Digital control from planning to proof.

Access historical shipment records, temperature curves, and Chain of Compliance reports in a single secure portal.

Durable and Sustainable Packaging

C3 packaging is built for repeat performance. The shipper’s durable structure meets ISTA 3A transit requirements, and recyclable outer packaging is included for every shipment to ensure a clean presentation.

Engineered for performance. Designed for sustainability.

Serialized components ensure traceability and requalification after every use, reducing waste and increasing supply chain confidence.

24/7/365 Monitoring and Support

Our expert logistics teams provide round-the-clock monitoring and support for every C3 shipment. In the event of a risk or delay, our teams take action immediately.

Always on. Always ready.

With decades of temperature-controlled logistics experience, we ensure your shipment stays on course and within temperature.

Delivering precision, protection, and peace of mind for every refrigerated and controlled room temperature (ambient) shipment.

Spec Sheet
Download the Cryoport Express C3 spec sheet for full details and specifications, including dimensions and storage capacity.

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Instructions
Download the Cryoport Express C3 shipping system loading and unloading instructions for details on managing samples.

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